Scientific Research on Maharishi Ayurveda 
    
Introduction and Overview of  Research 
    Maharishi  Ayurveda is a thorough and comprehensive revival of Ayurveda, the world’s most ancient  and complete system of natural health care.   Maharishi Ayurveda was introduced in 1980 by Maharishi Mahesh Yogi, the founder of Transcendental Meditation, in collaboration with India’s leading  Ayur-Vedic physicians and scholars [1-3].
            Maharishi’s  Vedic Approach to Health is the name given to the integrated system of health care that  includes both Transcendental Meditation and Maharishi Ayurveda, as parts of a  spectrum of approaches to improving health and well-being.
     This section summarizes results of scientific research  on Maharishi Ayurveda. Part I presents results of scientific Research on Transcendental Meditation.
    The goal of Maharishi Ayurveda is to restore  physiological balance by enlivening the inner intelligence of the body, which  underlies and governs its material structures and functions. 
     Knowledge of the body’s inner intelligence is  available in the Veda and Vedic literature, as brought to light by Maharishi  over the past 40 years. Based on Maharishi’s work in the field of  consciousness, recent research by Tony Nader MD PhD has demonstrated that the  patterns of intelligence contained in the Veda and Vedic Literature correspond  precisely to the structures and functions of the human physiology identified by  modern science  [3]. According to the  principles of Maharishi Ayurveda, enlivenment of the body’s inner intelligence  ensures that its innate capacity for balance, self-repair, and resistance to  disorder can be harnessed to the full. 
    The methods of Maharishi’s Vedic Approach to Health  include:
    
      - techniques for the full  development of consciousness, including Transcendental Meditation   (please refer to Scientific Research on Transcendental Meditation).
 
      -  balanced diet according to  individual need, with emphasis on promoting optimal digestion and metabolism of  food;
 
      -  natural herbal  preparations, which are designed to promote balance and enhance natural healing  processes without creating side-effects;
 
      -  physiological purification  procedures;
 
      -  self pulse reading—a simple  procedure for assessing the degree of balance or imbalance in the physiology,  thereby allowing timely adjustment of diet and behaviour in order to prevent  disorder;
 
      -  behavioural measures,  including guidelines for health-promoting daily and seasonal routines;
 
      -  suitable exercise according  to individual need; 
 
      -  programmes to reduce  collective stress and improve the collective health of society as a whole;
 
      -  architectural and planning  measures which ensure that the orientation and design of homes, work premises,  and communities are in tune with Natural Law and therefore do not generate  imbalance and disease;
 
      -  measures to ensure that  individual health is supported by natural cycles in the universe.
 
      - These methods are discussed in detail in the book Contemporary Ayurveda — Medicine and  Research in Maharishi Ayurveda [1].
 
    
    Below is an overview of the research done on  Maharishi Ayurveda products and treatments. A more detailed summary of each  of the individual research papers is available as a PDF download (21MB). 
    REDUCED HEALTH  CARE REQUIREMENTS  AND COSTS
     A recent study compared health care requirements and  costs over a four year period for 693 individuals using Maharishi’s Vedic  Approach to Health (Maharishi Ayurveda) in comparison to 4,148 matched control  subjects  Total medical expenditure per  capita was 59% lower for the group using Maharishi’s Vedic Approach to Health,  with lower health care utilization and costs across all age groups and for all  disease categories.  Compared to the  control group, hospital admission rates for subjects using Maharishi’s Vedic  Approach to Health were 11.4 times lower for cardiovascular disease, 3.3 times  lower for cancer, and 6.7 times lower for mental health and substance abuse.  The greatest reductions were seen in patients  over 45 years, who had 88% fewer patient days in hospital than controls [4].
    TRANSCENDENTAL  MEDITATION
     Extensive scientific research conducted at over 200  independent universities and research institutions has demonstrated that  regular practice of Transcendental Meditation has multiple benefits for health,  including: reduced requirements for medical care and reduced health care costs;  reduction of major risk factors for heart disease; decreased smoking and  reduced use of alcohol and non-prescribed drugs; improvement in hypertension,  angina pectoris, asthma, insomnia, and post-traumatic stress disorder; slowing  or reversal of deleterious  effects of  ageing; improved health, well-being, and longevity in elderly people; comprehensive  improvements in mental health including decreases in anxiety, depression,  hostility, and emotional instability, and growth of creativity, intelligence,  and positive personality characteristics; increased job satisfaction and  improved work performance; better relationships [5-20].
    These findings are summarised on the Research on TM page.
    HERBAL  PREPARATIONS 
     Herbal preparations known as Maharishi Ayurveda Rasayanas have  become the focus of increasing scientific scrutiny in recent years, with research  conducted at a number of universities in the United   States, Japan  and India.  According to the classical Ayur-Vedic texts, these preparations are formulated  to strengthen resistance to disease and prevent ageing. Research has focused  particularly on two compounds commonly recommended for their general preventive  and health-promoting effects, known as Maharishi  Amrit Kalash  [M-4 and M-5], although  other Maharishi Ayurveda preparations have also been studied [2].
    1. Laboratory  Studies
    A. Free  Radical Scavenging
     Particular interest has centred on the ability of Maharishi Ayurveda Rasayanas to  scavenge free radicals — small, highly reactive molecules or molecular  fragments which can powerfully oxidize and damage vital biomolecules, injuring  tissues and disrupting physiological repair mechanisms. Free radicals play a  central role in the ageing process and in many diseases, including coronary  heart disease, cancer, Alzheimer’s disease, diabetes mellitus, and inflammatory  conditions such as rheumatoid arthritis   [21]. 
     Research has shown that Maharishi Ayurveda  Rasayanas (including M-4, M-5, MA-631, and MA Students Rasayana) provide  exceptionally powerful protection against both free radicals and non-radical  oxidants, including highly effective scavenging of lipid peroxides, which play  a key role in the cascade of destruction caused by free radicals  [22-34] (see chart).
    
    B.  Cardiovascular Research
     Free radicals play an important role in the  causation of coronary heart disease and other cardiovascular disorders. In  particular, free radicals oxidize cholesterol and other fats to form oxidized  low density lipoprotein  [LDL], which  then accumulates in damaged arterial walls. In one study, four different  Maharishi Ayurveda Rasayanas (M-4, M-5, MA-631, and MA Coffee Substitute) were  each hundreds or thousands of times more powerful in preventing oxidation of  LDL than other known anti-oxidants, including vitamins C and E  [24, 29].
    
     More recently, reduced LDL oxidation has been  demonstrated in a clinical research study on people with elevated blood  cholesterol levels  (please refer to  section below on clinical research)   [33].
     A Maharishi Ayurveda compound (M-5) has been found  to prevent the aggregation of human blood platelets in response to four  different stimuli. Platelet aggregation contributes to both atherosclerosis and  thrombosis—the principal mechanisms leading to coronary heart disease,  myocardial infarction  (heart attack),  and various other cardiovascular disorders   [35].
    
     Another study found that addition of a Maharishi  Ayurveda herbal preparation (M-4) to the diet led to a 50 percent reduction in  coronary artery atherosclerosis in Watanabe rabbits, a species that is  genetically highly susceptible to this disorder   [36, 37].
      A clinical pilot study found improvements in  patients with angina pectoris  (chest  pain due to heart disease) who took two Maharishi Ayurveda Rasayanas (M-4 and  M-5) (please refer to section below on clinical research)  [38]. 
    C. Prevention  of Chemical Toxicity
     Maharishi Ayurveda herbal compounds (M-4, M-5, MA  Students Rasayana) have been found to protect against tissue damage caused by  the solvent toluene  (a potent inducer of  free radicals and a serious industrial health risk). M-4 and M-5 also decreased  toxicity due to adriamycin (a drug commonly used in the treatment of cancer,  which is a powerful generator of free radicals)   [22, 25, 31, 32]. Addition of Maharishi Ayurveda Rasayanas to the diet  led to increased survival rate in animals receiving adriamycin over a four week  period  [22]. 
     M-4 has also been found to enhance the glutathione  anti-oxidant system, a vital natural defence against toxins, and to prevent  damage to this system induced by the cancer drug cisplatin  [39].
    D. Research on  Cancer Prevention
     A number of studies have found that the Maharishi  Ayurveda compounds M-4 and M-5 reduce the development, growth, spread, and  mortality of cancer in laboratory animals   [40-43].
    
     Moreover, in one study M-5 induced both  morphological and biochemical differentiation of mouse neuroblastoma cells in  culture (thus promoting transformation of abnormal tumour cells towards normal,  mature nerve cells)  [44].
    E.  Immunological Research
     Maharishi Ayurveda Rasayanas (M-4 and M-5) have  been found to enhance the response to foreign antigens of two types of cell  that are fundamental to the immune system, without affecting their properties  when not challenged. T-lymphocytes showed enhanced proliferation in response to  mitogens together with increased production of interleukin-2, an immunomodulator  which plays a central role in immune responses. Macrophages showed increased  efficiency in killing tumor cells and enhanced production of nitric oxide,  which is used to kill bacteria and cancer cells   [45-49].
    2. Clinical  Research
     An uncontrolled clinical pilot study examined the effects of Maharishi  Ayurveda herbal preparations and other aspects of Maharishi Ayurveda in 126  patients suffering from one of ten common chronic disorders  [asthma, chronic bronchitis, rheumatoid  arthritis, chronic constipation, eczema, psoriasis, hypertension,  non-insulin-dependent diabetes, chronic sinusitis, chronic headaches]. 
      The average duration of these disorders was more  than 17 years. After three months of Maharishi Ayurveda treatment, 79% of patients  showed clear-cut improvements  [50].
    
    
      A controlled prospective study of Maharishi  Ayurveda herbal preparations (M-4 and M-5) in patients receiving multi-drug  chemotherapy for cancer found a reduced incidence of vomiting and diarrhoea,  and improved sleep, weight, and overall well-being compared to control  patients. Patients also showed reduced free radical activity  (as shown by decreased lipid peroxide levels)  and less haematological toxicity, indicated by maintenance of higher white  blood cell and platelets counts compared to controls  [51].
      In another clinical pilot study, patients with  angina pectoris  (chest pain due to heart  disease) who took two Maharishi Ayurveda Rasayanas (M-4 and M-5) showed  significant reductions in the frequency of chest pain and need for sublingual  anti-anginal medication, as well as increased well-being  [38].
     More recently, M-4 has been shown to prevent LDL  oxidation in people with elevated blood cholesterol levels  (oxidation of LDL plays in important role in  the development of atherosclerosis, especially in those with raised  cholesterol)  [33].
     A pilot trial of a Maharishi Ayurveda compound  (MA-471) traditionally purported to have anti-diabetic properties found  improved blood sugar control and reduced symptoms in patients with non-insulin  dependent diabetes mellitus  [2].
    3. Research on  Cognitive Performance and Perception
     A randomized placebo-controlled trial found that a  Maharishi Ayurveda Rasayana traditionally recommended for students led to  increased growth of intelligence quotient   (IQ) in school children over a five month period  [52]. Laboratory studies have shown that this  compound prevents free radical damage to brain tissue and promotes a  biochemical pathway thought to be important for learning and memory  [26, 53].
     Another randomized placebo-controlled trial found  that the herbal preparation Maharishi Amrit Kalash improved performance on a  complex measure of visual information processing that is known to deteriorate  with ageing [54]. This effect might be mediated by the free radical scavenging  properties of this preparation   (discussed above) or via interactions with specific neurohormone systems  in the brain  [55].
    PHYSIOLOGICAL  PURIFICATION THERAPIES
     Research on the Maharishi  Ayurveda Physiological Purification Programme has demonstrated benefits  for general health and well-being, mental health, and perception, and  reductions in cardiovascular risk factors. In one study, subjects who underwent  this treatment showed improvements in well-being, energy, stamina, appetite and  digestion, and increased feelings of youthfulness compared to control subjects  who received only health education over the same time period. In a second study  of similar design, subjects who received treatment showed reductions in anxiety,  depression and fatigue, and an increase in vigour compared to controls  [56]. Another investigation found increased  speed of visual information processing   [57].
    
     The Maharishi Ayurveda Physiological Purification  Programme has also been found to reduce risk factors for coronary artery  disease, including reduced serum cholesterol and increased HDL cholesterol  (which has a protective effect), reduced  lipid peroxides, increased levels of vasoactive intestinal peptide  (which dilates coronary arteries), and reductions  in pulse rate, diastolic blood pressure, and anxiety  [58]. Another study found reduced cholesterol  levels and increased emotional stability as a result of treatment  [59].
     A model has been developed to explain how these  purification procedures may produce their effects by removing toxins from the  body  [60].
    VEDIC SOUNDS
     Vedic sounds   (Sama Veda) have been found to decrease the growth of cancer cells lines  in the laboratory compared to a control condition, in contrast to the effect of  ‘hard rock’ music which tended to increase growth  [61].
    COLLECTIVE  HEALTH
     Maharishi’s Vedic Approach to Health recognises that  individual health cannot be divorced from the collective health of society.  More than 40 well-controlled studies have now shown that about 1% of the  population of a community practising Transcendental Meditation, or an even  smaller fraction practising the advanced TM-Sidhi programme, can lead to  reduction of negative tendencies (such as violence, crime, accidents, disease,  and suicides) and improvement in positive trends (such as economic prosperity)  for the whole society [62-75]. 
     Researchers have named this phenomenon the Maharishi  Effect, as it was predicted by Maharishi in 1960. Decreased crime rate in the  Merseyside region has been demonstrated as a result of this effect [74].
     In a published study, a well-designed  prospective experiment demonstrated a 23% reduction in violent crime in Washington DC  as a result of the Maharishi Effect — a result confirmed by a panel of  independent experts [75]. 
     Reduction in crime and other improvements in the  quality of life in society have direct benefits for the individual by reducing  collective stress and social disharmony, both of which are known to be major  factors influencing health standards in the general population.
 
List of Studies and Publications  on Maharishi Ayurveda
1.  Sharma HM, Clark C. Contemporary  Ayurveda — Medicine and research in Maharishi Ayurveda. Churchill  Livingstone, 1998.
2.  Sharma HM, Alexander CN. Maharishi Ayurveda: Research  Review. Complementary Medicine  International, 1996, 3 (2) 16-28.
3.  Nader T. Human  Physiology — Expression of Veda and Vedic Literature, 1995, Maharishi Vedic  University, Vlodrop, The Netherlands.
4.  Orme Johnson DW, Herron RE. An innovative approach to  reducing medical care utilization and expenditures. American Journal of Managed Care, 1997, 3: 135-144.
5.  Scientific Research on  Maharishi’s Transcendental Meditation and TM-Sidhi Programme: Collected Papers,  Volumes 1-6, Maharishi Vedic University Press, Holland.
6.  Orme-Johnson DW. Medical care utilization and the  Transcendental Meditation programme. Psychosomatic  Medicine, 1987, 49: 493-507.
7.  Herron RE, Hillis SL, Mandarino JV, Orne Johnson DW, Walton  KG. The impact of the Transcendental Meditation program on government payments  to physicians in Quebec. American Journal of Health Promotion,  1996, 10: 208-216.
8.  Schneider RH, Staggers F, Alexander CN, Sheppard W,  Rainforth M, Kondwani K, Smith S, King CG. A randomized controlled trial of  stress reduction for hypertension in older African Americans. Hypertension, 1995, 26: 820-827.
9.  Alexander CN, Schneider RH, Staggers F, Sheppard W,  Clayborne BM, Rainforth M, Salerno J, Kondwani K, Smith S, Walton KG, Egon B.  Trial of stress reduction for hypertension in older African Americans II — Sex  and risk subgroup analysis. Hypertension,  1996, 28: 228-237.
10.  Cooper M, Aygen M. Transcendental Meditation in the management  of hypercholesterolaemia. Journal of  Human Stress, 1979, 5: 24-27.
11. Alexander CN, Robinson P, Rainforth M. Treating and preventing  alcohol, nicotine, and drug abuse through Transcendental Meditation: A review  and statistical meta-analysis. Alcoholism  Treatment Quarterly, 1994, 11: 1-2, 13-87.
12. Herron RE, Schneider RH, Mandarino GV, Alexander CN, Walton  KG. Cost-effective hypertension management: comparison of drug therapies with  an alternative program. American Journal  of Managed Care, 1996, 2: 427-437.
13. Zamarra JW, Schneider RH, Besseghini I, Robinson DK, Salerno JW. Usefulness of  the Transcendental Meditation programme in the treatment of patients with  coronary artery disease. American Journal  of Cardiology, 1996, 77, 867-70.
14.  Brooks JS, Scarano T. Transcendental Meditation in the  treatment of post-Vietnam adjustment. Journal  of Counselling and Development, 1986, 64: 212-215.
15.  Alexander CN, Langer EJ, Davies JL, Chandler  HM, Newman RI. Transcendental Meditation, mindfulness,  and longevity: an experimental study with the elderly. Journal of Personality and Social Psychology, 1989, 57, 6: 950-964.
16.  Eppley K, Abrams A, Shear J. Differential effects of relaxation  techniques on trait anxiety: a meta-analysis. Journal of Clinical Psychology, 1989, 45: 957-74.
17.  Alexander CN, Gelderloos P, Rainforth MV. Transcendental  Meditation, self-actualization, and psychological health: a conceptual overview  and statistical meta-analysis. Journal of  Social Behavior and Personality, 1991, 6 (5): 189-247.
18.  Haratani T, Henmi T. Effects of Transcendental Meditation on  health behavior of industrial workers.  Japanese Journal of Public Health, 1990, 37: 729.
19.  Haratani T, Henmi T. Effects of Transcendental Meditation on  mental health of industrial workers. Japanese  Journal of Industrial Health, 1990, 32: 656.
20.  Alexander CN, Swanson GC, Rainforth MV, Carlisle  TW, Todd CC, Oates RM Jar. Effects of the Transcendental Meditation program on  stress-reduction, health, and employee development in two occupational  settings. Anxiety, Stress and Coping,  1993, 6: 245-262.
21.  Sharma HM. Freedom from  disease: How to control free radicals, a major cause of aging and disease.  Veda Publishing, 1993, Toronto.
22. Engineer FN, Sharma HM, and Dwivedi C. Protective effects of  Maharishi Amrit Kalash on adriamycin-induced microsomal lipid peroxidation and  mortality. Biochemical Archives,  1992, 8: 267-72.
23. Niwa Y. Effect of Maharishi-4 and Maharishi-5 on inflammatory  mediators with special reference to free radical scavenging effect. Indian Journal of Clinical Practice,  1991, 1: 23-27.
24. Sharma HM, Hanna AN, Kauffman EM, Newman AI. Inhibition of  human low-density lipoprotein oxidation in vitro by Maharishi Ayurveda herbal  mixtures. Pharmacology, Biochemistry  & Behaviour, 1992, 43: 1175-82.
25. Hanna AN, Sharma HM, Kauffman EM, Newman AI. In vitro and in  vivo inhibition of microsomal lipid peroxidation by MA-631. Pharmacology, Biochemistry & Behaviour,  1994, 48 (2): 505-510.
26. Hanna AN, Kauffman EM, Newman AI, Sharma HM. Prevention of  oxidant stress by student rasayana (SR). In:  Free Radicals in diagnostic medicine: A systems approach to laboratory  technologies, clinical correlations, and antioxidant therapy. D Armstrong  (Ed), Plenum Press, New York  1994, 444-445.
27. Dwivedi C, Sharma HM, Dobrowski S, Engineer FN. Inhibitory  effects of Maharishi-4 and Maharishi-5 on microsomal lipid peroxidation.  Pharmacology  Biochemistry & Behaviour, 1991, 39: 649-652.
28. Hanna AN, Sharma HM, Lubow  GP, Titterington LC, Stephens RE. Possible mechanism of action of Student  Rasayana for improving brain functioning. Federation  of American Societies of Experimental Biology Journal, 1994, 8(5): 658.
29. Sharma HM, Hanna AN,  Titterington LC, Stephens RE.  Effect of  MAK-4 and MAK-5 on endothelial cell- and soyabean lipoxygenase-induced LDL  oxidation. In Free Radicals in Diagnostic  Medicine: A Systems Approach to Laboratory Technologies, Clinical Correlations,  and Antioxidant Therapy. D. Armstrong (ed.). 1995, New York: Plenum Press.
30. Lee JY, Lott JA, Sharma HM.  Biochemical changes induced by Maharishi Amrit Kalash (MAK-4) and MA-208 in  diet-induced hypercholesterolemic rabbits. In Free Radicals in Diagnostic Medicine: A Systems Approach to Laboratory  Technologies, Clinical Correlations, and Antioxidant Therapy. D. Armstrong  (ed.). 1995, New York:  Plenum Press.
31. Bondy S, Hernandez TM, Mattia C. Anti-oxidant properties of  two herbal preparations. Biochemical  Archives, 1994, 10: 25-31.
32. Sharma HM, Hanna AN, Kauffman EM, Newman HAI. Effect of herbal  mixture Student Rasayana on lipoxygenase activity and lipid peroxidation. Free Radicals in Biology and Medicine,  1995, 18: 687-697.
33. Sundaram V, Hanna, AN, Lubow G, Falko J, Sharma HM. Increased  resistance of human LDL to oxidation in hyperlipidemic patients supplemented  with oral herbal mixture MAK-4. Federation  of American Societies of Experimental Biology Journal, 1995, 9(3): A141.
34. Lee JY.  The antioxidant  and antiatherogenic effects of MAK-4 in WHHL rabbits. PhD Dissertation.  1995, The Ohio State University, Columbus,   Ohio, USA.
35. Sharma HM, Feng Y, Panganamala RV. Maharishi Amrit Kalash  (MAK) prevents human platelet aggregation. Clinical  & Terapia Cardiovascular, 1989, 3: 227-230.
36. Lee JY, Lott, JA, Kauffman EM, and Sharma HM.  Effects of herbal mixture MAK-4 on organ  functions in WHHL rabbits. Biochemical  Archives, 1997, 13: 285-296.
37. Lee JY, Hanna AN, Lott, JA, and Sharma HM.  The antioxidant and antiatherogenic effects  of MAK-4 in WHHL rabbits. Journal of  Alternative and Complementary Medicine, 1996, 2(4): 463-478.].
38. Dogra J, Grover N, Kumar P, Aneja N. Indigenous free radical  scavenger MAK 4 and 5 in angina pectoris. Is it only a placebo? Journal of the Association of Physicians of  India, 1994, 42 (6).
39. Sharma HM, Guenther J, Abu-Ghazaleh, Dwivedi C. Effects of  Ayur-Vedic food supplement M-4 on cisplatin-induced changes in glutathione and  glutathione-S-transferase activity. Proceedings  of the XVI International Cancer Congress, Vol. 1, 1994, Rao RS, Deo MG,  Sanghvi LD. (eds.), pp. 589-592. Bologna (Italy): Monduzzi Editore.
40. Sharma HM, Dwivedi C, Satter BC, Gudehitihlu HA, Malarkey W,  Tejwani GA. Anti-neoplastic properties of Maharishi-4, against DMBA-induced  mammary tumours in rats. Pharmacology,  Biochemistry, and Behaviour, 1990, 35: 767-773.
41. Sharma HM, Krieger J, Dwivedi C. Antineoplastic properties of  dietary Maharishi-4 and Maharishi Amrit Kalash Ayurvedic food supplements. European Journal of Pharmacology, 1990,  183: 193.
42. Patel VK, Wang J, Shen RN, Sharma HM, Brahmi Z. Reduction of  metastasis of Lewis lung carcinoma by an Ayurvedic food supplement in mice. Nutritional Research, 12: 51-61, 1992.
43. Sharma HM, Dwivedi C, Satter  BC, Abou-Issa H. Antineoplastic properties of Maharishi Amrit Kalash, an  ayurvedic food supplement, against 7,12-dimethylbenz (a) anthracene-induced  mammary tumours in rats.  Journal of Research and Education in Indian  Medicine, 1991, 10(3): 1-8.  
44. Prasad KN, Edwards-Prasad J, Kentroti, S, Brodie C, and  Vernadakis A. Ayurvedic (science of life) agents induce differentiation in  murine neuroblastoma cells in culture. Neuropharmacology,  1992, 31: 599-607.
45. Dileepan KN, Varghese ST, Page JC, Stechschulte DJ. Enhanced  lymphoproliferative response, macrophage-mediated tumour cell killing, and  nitric oxide production after ingestion of an Ayurvedic drug. Biochemical Archives, 1993, 9: 365-374.
46. Dileepan KN, Patel V, Sharma HM, Stechschulte DJ. Priming of  splenic lymphocytes after ingestion of an Ayurvedic herbal food supplement:  evidence for an immunomodulatory effect. Biochemical Archives, 1990, 6:  267-274.
47. Inaba R, Sugiura H, Iwata H,  Mori H, Tanaka T. Immunomodulatory effects of Maharishi Amrit Kalash 4 in mice. Journal of Applied Nutrition, 1996,  48(1-2): 10-21.
48.  Inaba R, Sugiura H, Iwata H, Tanaka T. Dose-dependent  activation of immune function in mice by ingestion of Maharishi Amrit Kalash 5. Environmental Health and Preventive  Medicine, 1997, 2(1): 35-39. 
49.  Inaba R, Sugiura H, Iwata H. Immunomodulatory effects of  Maharishi Amrit Kalash 4 and 5 in mice. Japanese  Journal of Hygiene, 1995, 50: 901-905.
50. Janssen G. Maharishi Ayur-Ved in the treatment of ten common  chronic disorders — a pilot study. Nederlands Tijdschrift voor Integrale Geneeskunde, 1989, 5: 586-594.
51. Mishra NC, Sharma HM Chaturvedi A, Ramakant, Srivastav S, Devi  V, Kakkar P, Vishwanathan, Natu SM, and Bogra J. Anti-oxidant adjuvant therapy  using a natural herbal mixture (MAK) during intensive chemotherapy: reduction  in toxicity. A prospective study of 62 patients. Proceedings of the XVI International Cancer Congress, Vol. 1, 1994,  Rao RS, Deo MG, Sanghvi LD (eds.), pp. 3099-3102. Bologna (Italy): Monduzzi  Editore.
52. Nidich SI, Morehead P, Nidich RJ, Sands D, Sharma H. The  effect of Maharishi Student Rasayana on non-verbal intelligence. Personality and Individual Differences,  15 (5) 599-602, 1993.
53. Hanna AN, Sharma, HM, Lubow  GP, Titterington LC, Stephens RE. Possible mechanism of action of Student  Rasayana for improving brain functioning. Federation  of American Societies of Experimental Biology Journal, 1994,  8(5): 658.
54. Gelderloos P, Ahlstrom HHB, Orme-Johnson DW, Robinson DK,  Wallace RK, Glaser JL. Influence of a Maharishi Ayur-Vedic herbal preparation  on age-related visual discrimination. International  Journal of Psychosomatics, 1990, 37 (1-4): 29.
55.  Sharma HM, Hanissian S, Rattan AK, Stern SL, Tejwani GA. Effect  of Maharishi Amrit Kalash on brain opioid receptors and neuropeptides. Journal of Research and Education in Indian  Medicine, 1991, 10(1): 1-8.
56. Schneider RH, Cavanaugh KL, Kasture HS, Rothenberg S, Averbach  R, Robinson D, Wallace RK. Health promotion with a traditional system of  natural health care: Maharishi Ayurveda. Journal  of Social Behavior and Personality, 1990, 5(3): 1-27.
57. Nidich SI, Smith DE, Sands D, Sharma H, Nidich RJ, Barnes V,  Jossang S. Effect of Maharishi Ayur-Ved Panchakarma purification program on  speed of processing ability. Maharishi  International University, Fairfield, Iowa, USA.
58. Sharma HM, Nidich SI, Sands D, Smith DE. Improvement in  cardiovascular risk factors through Panchakarma purification procedures. Journal of Research and Education in Indian  Medicine, 1993, XII: 4, 2-13.
59. Waldschütz R. Veränderungen physiologischer und psychischer  Parameter durch eine ayurvedische Reinigungskur. Erfahrungsheilkunde - Acta Medica Empirica, 1988, 11: 720-729.
60. Smith DE, Salerno JW. A model for extraction of both  lipid-soluble and water-soluble toxins using a procedure from Maharishi  Ayurveda. Medical Hypotheses, 1992,  39: 1-5.
61. Sharma HM, Kauffman EM, Dudek A, Stephens RE. Effect of  different sounds on growth of human cancer lines in vitro. Alternative Therapies in Clinical Practice, 1996, 3 (4) 25-32.
62. Dillbeck M, Landrith G, Orme-Johnson D. The Transcendental  Meditation program and crime rate change in a sample of forty-eight cities. Journal of Crime and Justice, 1981, 4:  25-45.
63. Dillbeck M, Cavanaugh K, Glenn T, Orme-Johnson D, Mittlefeldt  V. Effects of Transcendental Meditation and the TM-Sidhi program on quality of  life indicators: Consciousness as a field. The  Journal of Mind and Behaviour, 1987, 8: 67-104.
64. Gelderloos P, Frid MJ, Goddard PH, Xue X, Loliger SA. Creating  world peace through the collective practice of the Maharishi Technology of the  Unified Field: improved US-Soviet relations. Social Science Perspectives Journal, 1988, 2(4): 80-94.
65. Orme-Johnson DW, Alexander CN, Davies JL, Chandler HM,  Larimore WE. International peace project in the Middle East: the effects of the  Maharishi Technology of the Unified Field. Journal  of Conflict Resolution, 1988, 32(4): 776-812.
66. Orme-Johnson DW, Alexander CN, Davies JL. The effects of the  Maharishi Technology of the Unified Field. Journal  of Conflict Resolution, 1990, 34(4): 756-868.
67. Dillbeck M, Banus CB, Polanzi C, Landrith GS. Test of a field  model of consciousness and social change: Transcendental Meditation and  TM-Sidhi program and decreased urban crime. The  Journal of Mind and Behaviour, 1989, 9(4): 457-486.
68. Dillbeck MC. Test of a field hypothesis of consciousness and  social change: time series analysis of participation in the TM-Sidhi program  and reduction of violent death in the U.S. Social  Indicators Research, 1990, 22: 399-418.
69. Orme-Johnson DW, Dillbeck M, Wallace RK, Landrith GS.  Intersubject EEG coherence: is consciousness a field? International Journal of Neuroscience, 1982, 16: 203-209.
70. Cavanaugh KL. Time series analysis of US and Canadian  inflation and unemployment: a test of a field theoretic hypothesis. Proceedings of the American Statistical  Association, Business and Economics Statistics Section, 1987, 799-804. Alexandria,  Virginia: American Statistical Association.
71. Cavanaugh KL, King KD. Simultaneous transfer function analysis  of Okun's misery index: improvement in the economic quality of life through  Maharishi's Vedic science and technology of consciousness. Proceedings of the American Statistical Association, Business and  Economics Statistics Section, 1988, 491-496. Alexandria, Virginia: American  Statistical Association.
72. Cavanaugh KL, King KD, Ertuna C. A multiple-input transfer  function model of Okun's misery index: an empirical test of the Maharishi  Effect. Proceedings of the American  Statistical Association, Business and Economics Statistics Section, 1989. Alexandria, Virginia:  American Statistical Association.
73. Cavanaugh KL, King KD, Titus BD. Consciousness and the quality  of economic life: empirical research on the macroeconomic effects of the  collective practice of Maharishi's Transcendental Meditation and TM-Sidhi  program. Proceedings of the Midwest Management Society, 1989, 183-190. Chicago: Midwest  Management Society.
74. Hatchard GD, Deans AJ, Cavanaugh KL, Orme Johnson DW. The  Maharishi Effect: A model for social improvement. Time series analysis of a  phase transition to reduced crime in Merseyside Metropolitan Area. Psychology, Crime and Law, 1996, 2:  165-174.
75. Hagelin JS, Rainforth MV, Orme-Johnson DW, Cavanaugh KL,  Alexander CN, Shatkin SF, Davies JL, Hughes AO, Ross E. Effects of group  practice of the Transcendental Meditation program on preventing violent crime  in Washington D.C.: Results of the National Demonstration  Project, June-July 1993. Social  Indicators Research, 47: 153-201.
Detailed summary available as a PDF download (21MB)